Xyril 25 typically refers to tablets containing 25 mg of Hydroxyzine Hydrochloride.  

Indications:

Xyril 25 (Hydroxyzine) is an antihistamine with anxiolytic (anti-anxiety) properties, used for:  

• Symptomatic relief of anxiety and tensionassociated with psychoneurosis and as an adjunct in organic disease states where anxiety is manifested.  
• Management of pruritus (itching) due to allergic conditions such as chronic urticaria, atopic and contact dermatoses, and histamine-mediated pruritus.  
• As a sedativewhen used as premedication and following general anesthesia.  

Pharmacology:

Hydroxyzine Hydrochloride is an H1 receptor antagonist. It works by suppressing activity in certain key regions of the subcortical area of the central nervous system. It also has antihistaminic, antiemetic, and some skeletal muscle relaxant properties.  

Dosage and Administration:

The dosage of Xyril 25 depends on the condition being treated and the age of the patient. Always follow your doctor's prescription.

Typical dosages are:

• Adults:
  • For anxiety and tension: 50-100 mg four times daily.  
  • For pruritus: 25 mg three to four times daily.  
  • As a sedative (premedication and following general anesthesia): 50-100 mg.
• Children (over 6 years):50-100 mg daily in divided doses.  

Side Effects:

Side effects are usually mild and transient. More common side effects include:   

• Drowsiness  
• Dry mouth  
• Blurred vision  
• Headache  
• Psychomotor impairment  

Precautions:

• Exercise caution when using with other CNS depressants and alcohol due to potential potentiation of effects.  
• Use with caution in patients with renal or hepatic impairment (dosage adjustment may be needed).
• May cause drowsiness; caution patients about driving or operating machinery.  

Contraindications:

Xyril 25 is contraindicated in patients with:

• Known hypersensitivity to hydroxyzine.  
• Early pregnancy.
• Nursing mothers.
• Prolonged QT interval.  

Pregnancy & Lactation:

Hydroxyzine is contraindicated in early pregnancy. It is not recommended for nursing mothers.

Drug Interactions:

May potentiate the effects of narcotics, barbiturates, and other CNS depressants. Avoid concurrent use with MAO inhibitors.

Storage:

Store in a cool and dry place, protected from light. Keep out of the reach of children.

Therapeutic Class:

Sedating Anti-histamine.

Important Note: This information is for general knowledge and informational purposes only and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.