Xetril 0.5

Presentation: Each tablet contains Clonazepam BP 0.5 mg. Tablets are usually uncoated or film-coated and supplied in blister packs or strips.

Indications: Xetril is indicated for the treatment of panic disorder, with or without agoraphobia. It is also indicated alone or as an adjunct in the treatment of the Lennox-Gastaut Syndrome (petit mal variant), akinetic, and myoclonic seizures. It may be indicated in patients with absence seizures (petit mal) who have failed to respond to succinimides.  

Dosage and Administration: Dosage must be individualized.

• Panic Disorder (Adults): The initial dose is 0.25 mg twice daily. After three days, the dose may be increased to 1 mg per day as needed.
• Seizure Disorders (Adults): The initial dose should not exceed 1.5 mg per day, divided into three doses. Dosage may be increased in increments of 0.5 to 1 mg every three days until seizures are adequately controlledor until side effects preclude any further increase. The maximumrecommended daily dose is 20 mg.
• Seizure Disorders (Pediatric Patients):To minimize drowsiness, the initial dose for infants and children (up to 10 years of age or 30 kg of body weight) should be between 0.01 and 0.03 mg/kg/day, but not to exceed 0.05 mg/kg/day given in two or three divided doses.  

Follow the physician's instructions carefully.

Side Effects: The most common side effects are related to central nervous system depression, including drowsiness and ataxia. Other possible side effects include behavioral problems, abnormal eye movements, confusion, depression, amnesia, and hallucinations.

Precautions: Xetril should not be used in patients with a history of hypersensitivity to benzodiazepines or those with significant liver disease. It can be administered to patients with open-angle glaucoma who are receiving appropriate treatment but should not be used in cases of acute narrow-angle glaucoma.Use with caution in patients with chronic respiratory insufficiency, renal dysfunction, and in elderly or debilitated patients. May be habit-forming. Avoid abrupt discontinuation. Use with caution during pregnancy and breastfeeding.

Drug Interactions: Xetril does not appear to affect the pharmacokinetics of phenytoin, carbamazepine, or phenobarbital. The effect of Xetril on the metabolism of other drugs has not been investigated.The depressant effects may be additive with other CNS depressants, including alcohol.

Storage: Store below 30°C, protected from light and moisture. Keep out of reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.