Metsina Suspension - (200mg/5ml)

Presentation: Each 5 ml of Metsina Suspension contains Metronidazole Benzoate BP equivalent to Metronidazole 200 mg. Available in bottles of 60 ml.

Indications:Metsina (Metronidazole) is an antibiotic and antiprotozoal medication used to treat infections caused by bacteria and parasites. It is indicated for:  

• The prevention of post-operative infections due to anaerobic bacteria.
• The treatment of septicaemia, bacteraemia, peritonitis, brain abscess, pelvic abscess, pelvic cellulitis, and post-operative wound infections caused by anaerobes.  
• Urogenital trichomoniasis.  
• Bacterial vaginosis (also known as non-specific vaginitis).  
• All forms of amoebiasis (intestinal, extra-intestinal disease, and that of symptomless cyst passers).  
• Giardiasis.  
• Acute ulcerative gingivitis.  
• Anaerobically infected leg ulcers and pressure sores.  
• Acute dental infections due to anaerobic organisms.  
• Antibiotic-associated pseudomembranous colitis.  

Pharmacology:Metronidazole is a member of the imidazole class of antibacterial drugs and is classified therapeutically as an antiprotozoal agent.The 5-nitro group ofMetronidazole is reduced by anaerobes metabolically.The reduced form interacts with DNA and causes bactericidal action.  

Dosage and Administration: Dosage depends on the condition being treated and the age and weight of the patient. Always follow your doctor's prescription.

• Adults & Children over 10 years:
  • Trichomoniasis: 200 mg three times daily or 400 mg twice daily for 7 days; or 800 mg in the morning and 1-2 gm at night for 2 days; or 2 gm as a single dose for 1 day.
  • Intestinal amoebiasis: 800 mg three times daily for 5 days.
  • Extra-intestinal & Asymptomatic amoebiasis: 400-800 mg three times daily for 5-10 days.
  • Giardiasis: 2 gm once daily for 3 days or 400 mg three times daily for 5-7 days.
  • Acute ulcerative gingivitis: 200 mg three times daily for 3 days.
  • Anaerobic infections: Loading dose of 800 mg followed by 400 mg every 8 hours.
• Children:
  • Trichomoniasis: Children 7-10 years: 100 mg three times daily; Children 3-7 years: 100 mg twice daily; Children 1-3 years: 50 mg three times daily for 7 days.
  • Intestinal amoebiasis: Children 7-10 years: 400 mg three times daily; Children 3-7 years: 200 mg four times daily; Children 1-3 years: 200 mg three times daily for 5 days.
  • Giardiasis: Children 7-10 years: 1 gm once daily; Children 3-7 years: 600-800 mg once daily; Children 1-3 years: 500 mg once daily for 3 days.  
  • Acute ulcerative gingivitis: Children 7-10 years: 100 mg three times daily; Children 3-7 years: 100 mg twice daily; Children 1-3 years: 50 mg three times daily for 3 days.  
  • Anaerobic infections: 7.5 mg/kg body weight every 8 hours.
• Metsina Suspension should be taken on an empty stomach, at least 1 hour before meals. Shake the bottle well before each use.

Side Effects:Common side effects may include nausea, vomiting, diarrhoea, metallic taste, and headache.Metsina may darken urine.  

Precautions:Avoid alcohol consumption during treatment and for at least one day afterwards due to the possibility of a disulfiram-like reaction. Use with caution in patients with CNS diseases or hepatic impairment.  

Pregnancy & Lactation: Metsina is generally considered safe to use during pregnancy. Use with caution during breastfeeding; breastfeeding should be held until treatment is finished. Consult your doctor.

Storage: Store below 30°C, protected from light. Keep out of the reach of children.

Therapeutic Class:Amoebicides, Anti-diarrhoeal Antiprotozoal.  

Important Note: This information is for general knowledge and informational purposes only and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.