Meglu 500

Presentation: Tablets containing 500 mg of metformin hydrochloride.

Indications: Meglu 500 is an oral antidiabetic drug belonging to the biguanide class. It is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Itcan be used as monotherapy or in combination with other antidiabeticagents such as sulfonylureas, thiazolidinediones, DPP-4 inhibitors, SGLT2 inhibitors, or insulin.

Dosage and Administration: The usual starting dose of metformin is 500 mg or 850 mg once or twice daily, given with meals. Meglu 500 is often used as a starting or maintenance dose. The maximum recommended daily dose of metformin is 2550 mg, usually given in divided doses. Your doctor will determine the appropriate starting dose and may gradually increase it based on your blood glucose response and tolerability. Meglu 500 tablets should be swallowed whole and should not be crushed or chewed. Take it with meals to reduce gastrointestinal side effects. Follow your doctor's instructions carefully.

Side Effects: Common side effects of metformin include gastrointestinal disturbances such as nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. These side effects are usually mild and transient, occurring more frequently during the start of treatment and subside over time. Lactic acidosis is a rare but serious metabolic complication that can occur with metformin use, especially in patients with kidney problems. Symptoms include nausea, vomiting, abdominal pain, muscle cramps, severe tiredness, and difficulty breathing. If you experience any of these symptoms, seek immediate medical attention.

Precautions:

• Inform your doctor about any pre-existing medical conditions, especially kidney disease, liver disease, heart failure, or any serious acute medical illness that can affect kidney function (such as dehydration, severe infection, or shock).
• Metformin is contraindicated in patients with severe renal impairment (eGFR < 30 mL/min).
• Temporary discontinuation of metformin may be necessary before surgical procedures or radiological studies involving iodinated contrast agents, as these can potentially worsen kidney function.
• Excessive alcohol intake should be avoided while taking Meglu 500, as it can increase the risk of lactic acidosis.
• Inform your doctor if you are pregnant or breastfeeding, as metformin use during these periods may require careful consideration.
• Be aware of potential drug interactions and inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements.  

Storage:   Store below 30°C, protected from light and moisture. Keep out of the reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.