Emeren Syrup (4mg/5ml)

• Brand Name: Emeren

• Manufacturer: Renata Limited

• Presentation:* Emeren Oral Solution 4 mg/5 ml

• Generic Name: Ondansetron

Indications:

Emeren is a serotonin subtype 3 (5-HT3) receptor antagonist indicated for:

• Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy.

• Prevention and treatment of post-operative nausea and vomiting.

• Prevention of radiotherapy-induced nausea and vomiting.

Pharmacology:

Ondansetron is a potent, highly selective 5HT3 receptor-antagonist. Its precise mode of action in controlling nausea and vomiting is not known. Chemotherapeutic agents and radiotherapy may cause the release of 5HT in the small intestine, initiating a vomiting reflex by activating vagal afferents via 5HT3 receptors. Ondansetron blocks the initiation of this reflex.

Dosage:

• Prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy:

  • Pediatric (4-11 years): 5 ml (4 mg) Emeren Oral Solution should be taken 30 minutes before the start of chemotherapy. The other 2 doses should be taken 4 and 8 hours after the first dose. Then 5 ml oral solution should be administered 3 times a day (every 8 hours) for 1-2 days after completion of chemotherapy.

• Prevention of radiotherapy-induced nausea and vomiting:

  • The recommended adult dosage is 10 ml (8 mg) Emeren Oral Solution 3 times daily.

Please note that It is important to consult a healthcare professional for specific medical advice and dosage instructions.