Eletam 500

Presentation: Tablets containing 500 mg levetiracetam.

Indications:Indicated as adjunctive therapy in the treatment of:  

• Partial-onset seizures with or without secondary generalization in adults and children4 years of age and older with epilepsy. 
• Myoclonic seizures in adults and adolescents 12 years of age and older with juvenile myoclonic epilepsy. 
• Primary generalized tonic-clonic seizures inadults and children 6 years of age and older with idiopathic generalized epilepsy.  

Mayalso be used as monotherapy in certain patients with partial-onset seizures.

Dosage and Administration: Dosage is individualized based on age, weight, renal function, and the condition being treated.

• Partial-onset seizures: Adults and adolescents ≥16 years: Initial 500 mg twice daily, may increase by 500 mg twice daily every 2 weeks to max 3000 mg daily. Children 4-15 years: Initial 10 mg/kg twice daily, may increase by 10 mg/kg twice daily every 2 weeks to max 60 mg/kg daily.
• Myoclonic seizures: Adults and adolescents ≥12 years: Initial 500 mg twice daily, may increase by 500 mg twice daily every 2 weeks to max 3000 mg daily.
• Primary generalized tonic-clonic seizures: Adults and adolescents ≥12 years: Initial 500 mg twice daily, may increase by 500 mg twice daily every 2 weeks to max 3000 mg daily. Children 6-15 years: Initial 10 mg/kg twice daily, may increase by 10 mg/kg twice daily every 2 weeks to max 60 mg/kg daily.

Adjustments are necessary in patients with impaired renal function. Can be taken with or without food. Follow physician's specific instructions.

Side Effects: Common side effects may include somnolence (sleepiness), asthenia (lack of energy), headache, dizziness, and accidental injury. Behavioral abnormalities such as irritability, agitation, depression, and aggression have been reported, particularly in pediatric patients. Patients and caregivers should be monitored for notable changes in behavior and mood.

Precautions: Use with caution in patients with pre-existing behavioral problems or psychiatric disorders. May cause somnolence and fatigue; patients should be advised not to drive or operate hazardous machinery until they are reasonably certain that levetiracetam does not affect them adversely. Gradual withdrawal is recommended to minimize the risk of increased seizure frequency.

Storage: Store below 30°C, in a dry place, protected from light and moisture. Keep out of reach of children.

Important Note: This information is for general knowledge only, not medical advice. Consult your doctor or pharmacist for specific guidance.