Carticare Max: Dual-Action Support for Joint Health

Carticare Max is a prescription tablet indicated for the management of various bone and joint conditions, specifically osteoarthritis, rheumatoid arthritis, and general bone and joint injuries.

How Carticare Max Works (Pharmacology)

Carticare Max combines two active ingredients,Glucosamine and Diacerein, which work together to support cartilage health, reduce inflammation, and alleviate pain.  

• Glucosamine: Glucosamine (2-amino-2-deoxy-alpha-D-glucose) is a natural amino sugar and a fundamental building block for the biosynthesis of glycosaminoglycans (GAGs), such as Hyaluronic Acid, Keratan Sulfate, and Chondroitin Sulfate. GAGs bind with proteins to form proteoglycans, which are essential components of articular cartilage. In osteoarthritis, cartilage deteriorates. Supplementing with Glucosamine Sulfate increases the body's Glucosamine levels, facilitating the production and repair of cartilage. It also activates chondrocytes (cartilage cells) to produce more GAGs and proteoglycans. About 90% of orally administered glucosamine sulfate is absorbed, primarily metabolized by the liver, and excreted through urine.  
• Diacerein: Diacerein is used for the treatment of osteoarthritis and also possesses analgesic (pain-relieving), antipyretic (fever-reducing), and anti-inflammatory activities. It works by inhibiting the synthesis of Interleukin-1 (IL-1), a key cytokine involved in cartilage destruction. Due to its specific mode of action, Diacerein has demonstrated disease-modifying effects in experimental models and in human subjects with finger joint and knee osteoarthritis. Its oral bioavailability is about 56%, and absorption is increased by approximately 25% when taken with food, making it best administered with meals. Diacerein is extensively metabolized (100%) in the liver, with urinary excretion of its metabolites ranging between 35% and 60%.  

Key Indications & Benefits

• Osteoarthritis: Helps improve cartilage health and reduce symptoms.  
• Rheumatoid Arthritis: Provides support in managing joint inflammation and pain.  
• Bone and Joint Injuries: Assists in recovery and provides relief for injuries affecting bones and joints.  

Always consult a registered physician for medication use.

Dosage & Administration

• Adults: One tablet twice daily, taken with food.  
• Children and Adolescents: The safety and effectiveness in children and adolescents under 18 years of age have not been established.  

Always consult a registered physician for medication use.

Important Considerations & Warnings

It is crucial to discuss your full medical history with your doctor before taking Carticare Max.  

Contraindications:

• Hypersensitivity (allergy) to Glucosamine or Diacerein.  
• Pregnancy and Breastfeeding: This tablet is contraindicated during pregnancy and breastfeeding.  

Side Effects:

• No serious adverse effects have been commonly reported.  
• Possible side effects include:  
  • Nausea  
  • Vomiting  
  • Diarrhea  
  • Epigastric pain (upper abdominal pain)  
  • Headache  
  • Skin rashes  
  • Intense yellow coloring of urine (due to Diacerein metabolites, a harmless effect).  

Interactions:

• Antacids (containing aluminium and/or magnesium hydroxide): Can decrease the absorption of Diacerein.  
• Laxatives or Antibiotics: May increase the risk of diarrhea when taken concomitantly.  

Precautions & Warnings:

• Caution should be exercised when administering this tablet to patients who are allergic to Glucosamine or Diacerein.  

Overdose Effects:

• There is no specific data available regarding overdose of Carticare Max. In case of suspected overdose, seek medical attention immediately.  

Storage Conditions

Store in a cool and dry place below 30°C, protected from light and moisture. Keep out of reach of children.