Aride 200 is a tablet containing 200 mg of Amisulpride. It is manufactured by Renata Limited in Bangladesh.

Indications:

Aride is used to treat acute and chronic schizophrenic disorders, characterized by positive symptoms (such as delusions, hallucinations, and thought disorders) and/or negative symptoms (such as blunted affect, emotional and social withdrawal). It is also indicated for the treatment of postoperative nausea and vomiting (PONV) in adults.

Dosage and Administration:

• For acute psychotic episodes, the recommended oral dose is between 400 mg/day and 800 mg/day, which may be adjusted up to 1200 mg/day based on individual response. Doses above 800 mg/day are not typically more effective and may increase side effects. It is preferable to administer the dose before a meal.
• For patients with mixed positive and negative symptoms, the dose should be adjusted to achieve optimal control of positive symptoms.
• For the prevention of postoperative nausea and vomiting, the intravenous dose is 10 mg as a single injection infused over 1 to 2 minutes.
• For the treatment of postoperative nausea and vomiting in patients who have received prophylaxis with a different antiemetic class or no prophylaxis, the intravenous dose is also 10 mg as a single injection infused over 1 to 2 minutes.

Side Effects:

Common side effects may include:

• Trembling, muscle stiffness or spasm, slow movement, producing more saliva than usual or feeling restless.
• Movements that the patient cannot control, mainly of the head, neck, jaw, or eyes. 
• Difficulty sleeping (insomnia) or feeling anxious or agitated. 
• Feeling drowsy or sleepy. 
• Constipation. 
• Feeling or being sick(nausea or vomiting).
• Dry mouth. 
• Putting on weight. 
• Low blood pressure, dizziness. 
• Difficulty reaching orgasm. 
• Blurred vision. 
• Increased blood levels of prolactin.  

Aride can also cause an increase in plasma prolactin levels, which may lead to galactorrhoea, amenorrhoea, gynaecomastia, breast pain, orgasmic dysfunction, and impotence.

Precautions:

Aride is contraindicated in individuals with:

• Hypersensitivity to amisulpride or any other ingredients in the drug.
• Concomitant prolactin-dependent tumors (e.g., pituitary gland prolactinomas and breast cancer).
• Pheochromocytoma.
• Children up to puberty.
• Pregnancy and lactation.

Use with particular caution in elderly patients due to a possible risk of hypotension or sedation. Dosage adjustment is recommended in patients with renal impairment based on creatinine clearance levels. Avoid consuming alcohol while taking Aride as it can cause CNS depression. Exercise caution while driving or operating machinery as Aride may cause drowsiness or dizziness.

Important Note: This information is for general knowledge and informational purposes only and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.