Xolitra

Generic Name:Flupentixol + Melitracen  

Strength:0.5 mg + 10 mg  

Dosage Form:Tablet  

Manufacturer:Beacon Pharmaceuticals PLC.  

Indication:

Xolitra is indicated for anxiety, depression, apathy, psychogenic depression, depressive neuroses, masked depression, psychosomatic affections accompanied by anxiety and apathy, menopausal depressions, dysphoria, and depression in alcoholicsand drug addicts.  

Dosage and Administration:  

For adults, the usual dose is 2 tablets daily in the morning and noon.In severe cases, the morning dose can be increased to 2 tablets. For elderly patients, the usual dose is 1 tablet in the morning.The maintenance dose is usually 1 tablet in the morning. In cases of insomnia or severe restlessness, a sedative may be added during the acute phase.  

Side Effects:

Side effects are rare at recommended doses and may include transient restlessness and insomnia.  

Precautions:

This tablet may enhance the effects of alcohol, barbiturates, and other CNS depressants. Simultaneous use with MAO inhibitors may cause hypertensive crises and should be avoided within two weeks of MAO inhibitor use. It may reduce the antihypertensive effect of guanethidine and similar drugs and enhance the effects of adrenaline and noradrenaline. Use with caution in patients previously treated with sedating tranquilizers, withdrawing them gradually. Not recommended for excitable or overactive patients. Preferably avoid during pregnancy and lactation.

Contraindications:

Contraindicated in the immediate recovery phase after myocardial infarction, bundle-branch conduction defects, untreated narrow-angle glaucoma, and acute alcohol, barbiturate, or opiate intoxication.