Vomix DR Tablet - (10mg+10mg)

Generic Name: Doxylamine Succinate + Pyridoxine Hydrochloride

Manufacturer: Beximco Pharmaceuticals Ltd.

Strength: Each delayed-release tablet contains Doxylamine Succinate USP 10 mg and Pyridoxine Hydrochloride USP 10 mg.

Indications:

• Vomix DR is indicated for the treatment of nausea and vomiting of pregnancy in women who do not respond to conservative management.

Dosage and Administration:

• The usual starting dose is two tablets orally at bedtime (Day 1).
• If this dose adequately controls symptoms the next day, continue taking two tablets daily at bedtime only.
• If symptoms persist on Day 2, increase the daily dose to one tablet in the morning and two tablets at bedtime (Day 3).
• If nausea and vomiting are controlled on Day 3, continue taking one tablet in the morning and two tablets at bedtime.
• If symptoms persist on Day 3, the dose may be further increased to a maximum of one tablet in the morning, one tablet in the afternoon, and two tablets at bedtime (Day 4).
• Do not exceed the maximum dose of four tablets (1 in the morning, 1 in the mid-afternoon, and 2 at bedtime) in 1 day.
• Vomix DR should be taken on an empty stomach with a glass of water.
• Swallow the tablets whole. Do not crush, chew, or split them.
• Take daily and not on an as-needed basis.

Contraindications:

Vomix DR is contraindicated in women with any of the following conditions:

• Known hypersensitivity to doxylamine succinate, other ethanolamine derivative antihistamines, pyridoxine hydrochloride, or any inactive ingredient in the formulation.
• Concurrent use of monoamine oxidase inhibitors (MAOIs) as they can intensify and prolong the anticholinergic effects of antihistamines.

Side Effects:

• Common: Somnolence (drowsiness).
• Other possible side effects: Dizziness, nervousness, stomach pain, headache, diarrhea, irritability, insomnia.
• Serious side effects: Allergic reactions (including skin rash, hives, swelling, trouble breathing). If any severe or unusual side effects occur, seek immediate medical attention.

Precautions:

• Vomix DR may cause somnolence. Avoid activities requiring complete mental alertness, such as driving or operating heavy machinery, until you know how the medication affects you.
• Use with caution in women with asthma, increased intraocular pressure, narrow-angle glaucoma, stenosing peptic ulcer, pyloroduodenal obstruction, or urinary bladder-neck obstruction due to its anticholinergic properties.
• Alcohol and other CNS depressants: Concurrent use is not recommended as it may increase drowsiness.

Use in Pregnancy & Lactation:

• Pregnancy: Vomix DR is intended for use in pregnant women and is classified as Pregnancy Category A.
• Lactation: Both doxylamine succinate and pyridoxine hydrochloride are excreted into breast milk. Caution should be exercised while breastfeeding.

Storage:

• Store below 30°C in a dry place, protected from light.
• Keep out of reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.