Sylvia ODT 75mg Tablet

Presentation: Each box contains 1x4's tablet in a blister pack.

Indications: Sylvia ODT (Rimegepant) is a calcitonin gene-related peptide (CGRP) receptor antagonist indicated for the:

• Acute treatment of migraine with or without aura in adults.  
• Preventive treatment of episodic migraine in adults.

Dosage and Administration:  

• Acute Treatment of Migraine: The recommended dose of Sylvia ODT is 75 mg taken orally, as needed. The maximum dose in a 24-hour period is 75 mg. The safety of using more than 18 doses in a 30-day period has not been established.
• Preventive Treatment of Episodic Migraine: The recommended dosage of Sylvia ODT is 75 mg taken orally every alternate day.

Contraindications: Sylvia ODT is contraindicated in patients with a history of hypersensitivity reaction to rimegepant, Sylvia ODT, or any of its components.  

Side Effects: Allergic reactions, including trouble breathing and rash, can happen after taking Sylvia ODT. The most common side effects of Sylvia ODT are nausea, stomach pain, and indigestion. 

Precautions: Hypersensitivity reactions, including dyspnea and rash, have occurred with Sylvia ODT and can occur days after administration. Avoid use of Sylvia ODT in patients with severe hepatic impairment and end-stage renal disease.

Drug Interactions:

• CYP3A4 Inhibitors: Concomitant administration of Sylvia ODT with strong inhibitors of CYP3A4 results in a significant increase in rimegepant exposure. Avoid concomitant administration.  
• CYP3A Inducers: Concomitant administration of Sylvia ODT with strong or moderate inducers of CYP3A can result in a significant reduction in rimegepant exposure, which may lead to loss of efficacy. Avoid concomitant administration. 
• P-gp Inhibitors: Avoid another dose of Sylvia ODT within 48 hours when it is concomitantly administered with potent inhibitors of P-gp.

Storage: Do not store above 25°C. Protect from light. Keep out of reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.