Rufecta Oral Solution contains Rupatadine Fumarate 5 mg per 5 ml. It is manufactured by Biopharma Limited. 

Indications:

Rufecta Oral Solution is indicated for the symptomatic treatment of:

• Seasonal allergic rhinitis (hay fever) in children aged 2 to 11 years.
• Perennial allergic rhinitis (year-round allergies) in children aged 2 to 11 years.
• Urticaria (hives) in children aged 2 to 11 years. 

Pharmacology:

Rupatadine is a long-acting, non-sedative antihistamine that selectively blocks peripheral H1 receptors.It also antagonizes the platelet-activating factor (PAF), both of which contribute to allergic and inflammatory processes. 

Dosage and Administration:

Children aged 2 to 11 years:

• Children weighing 25 kg or more:5 ml (5 mg of rupatadine) of the oral solution once daily, with or without food. 
• Children weighing equal or more than 10 kg to less than 25 kg:2.5 ml (2.5 mg of rupatadine) of the oral solution once daily, with or without food. 

Contraindications:

Hypersensitivity to rupatadine or any of the excipients. 

Side Effects:

Common:

• Drowsiness 

Uncommon:

• Increased appetite
• Irritability
• Nasal dryness
• Malaise

Pregnancy and Lactation:

The safety of Rupatadine during pregnancy and lactation has not been established. It should only be used if the potential benefit outweighs the potential risk.

Precautions and Warnings:

Rufecta Oral Solution should be used with caution in children with:

• Known prolongation of the QT interval. 
• Uncorrected hypokalemia. 
• Ongoing proarrhythmic conditions. 
• Impaired kidney or liver function (use is currently not recommended due to lack of clinical experience). 

Drug Interactions:

• The concomitant administration of rupatadine with ketoconazole or erythromycin (CYP3A4 inhibitors) increases systemic exposure to rupatadine and should be used with caution. 
• Grapefruit and grapefruit juice should not be taken simultaneously with rupatadine as they can increase the levels of rupatadine in the body. 

Storage Conditions:

Store in a cool and dry place below 30°C, protected from light and moisture. Keep out of reach of children.

Note: This information is for general knowledge and informational purposes only and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your child's medication.