Migrium 5 Tablet

Generic Name: Flunarizine Hydrochloride

Manufacturer: OSL Pharma Limited

Strength: Available in 5 mg tablets.

Indications:

• Prevention of migraine headaches (classic with aura or common without aura).
• Symptomatic treatment of vestibular vertigo (dizziness) due to diagnosed functional disorder of the vestibular system. 
• Peripheral Vascular Disease (PVD). 
• Motion sickness. 
• Refractory epilepsy (resistant to other treatments).

Dosage and Administration:

• Dosage varies depending on the condition being treated and patient age.
• Migraine Prophylaxis:
  • Starting dose for adults under 65: 10 mg at night.
  • Starting dose for adults over 65: 5 mg daily.
  • If effective after 2 months, the dose may be reduced for maintenance.
  • Treatment should be interrupted after 6 months and restarted only if migraines return.
• Vertigo and Motion Sickness: 10-20 mg daily for adults, 5 mg daily for children (>40 kg).
• Peripheral Vascular Disease: 10 mg twice daily, up to 30 mg per day if needed.
• Epileptic Seizure: 15-20 mg daily for adults, 5-10 mg daily for children (as add-on therapy).
• May be taken with or without food.

Contraindications:

• Hypersensitivity to flunarizine.
• History of depressive illness.
• Pre-existing symptoms of Parkinson's disease or other extrapyramidal disorders.

Side Effects:

• Common: Drowsiness, fatigue, weight gain, increased appetite.
• Less Common: Depression (especially in those with a history), extrapyramidal symptoms (tremors, stiffness, slow movement), heartburn, nausea, stomach pain, insomnia, anxiety, dry mouth, muscle ache, skin rash, milky discharge from nipples (galactorrhea).

Precautions:

• May cause drowsiness, avoid driving or operating machinery until you know how it affects you.
• Alcohol and other CNS depressants can worsen drowsiness.
• Use with caution in the elderly.
• Use with caution in patients with liver disease.
• Inform your doctor if you have a history of depression.
• Migraine attacks may still occur while taking Migrium; do not increase the dose to treat an acute attack.

Use in Pregnancy & Lactation:

• Consult your doctor before using if pregnant or breastfeeding.

Storage:

• Keep below 30°C, away from light and moisture.
• Keep out of reach of children.

Important Note: This information is for general knowledge and informational purposes only, and does not substitute professional medical advice. Always consult your doctor or pharmacist for specific instructions and guidance regarding your medication. They can assess your individual medical condition and provide the most appropriate advice.